Last modified: Thu Apr 15 16:54:24 BST 2004
Updated by Kirill Degtyarenko
Last modified: Thu Apr 15 16:54:24 BST 2004
For a list of corresponding EC numbers, click here.
P450 enzymes constitute a superfamily of haem-thiolate proteins, widely distributed in bacteria, fungi, plants and animals. The enzymes are involved in metabolism of a plethora of both exogenous and endogenous compounds. Usually, they act as terminal oxidases in multicomponent electron transfer chains, called here P450-containing monooxygenase systems.
Gene Species PIR SwissProt GenBank/EMBL/DDBJ PRF
CYP1A1 hum B23585 A24797 P04798 M12079 X04300 X02612 K03191 1210238A
S15803 S16714 D12525 D01198 D10855 D01150
mon S21761 P33616 1814274A
Mir Q29489 D17575
rat A00185 S15584 P00185 K02246 M12170 M14633 M26126 1005262A
M26129 X00469 1010319A
1105202A
1713486A
ham JX0189 Q00557 D10251 D12977 1803390A
gpi F24406 Q06367 D11043 2001208A
rab A27821 B27821 P05176 D00212 M11727 X05685 1109280B
1307202A
Q28716 M19917
cat U82184
dog C37222 1703408B
she S79795
tro P10609 M21310 1410185A
CYP1A1/A3 tro A28789
Cyp1a-1 mou A00184 S15588 P00184 Y00071 M10021 K02588
A23923
Cyp1a-1p mou M11515
CYP1A2 hum S07373 S16718 Q16754 L00383 L00384 L00385 L00386 1210358A
S22433 L00387 L00388 L00389 1918405A
P05177 M12078 M14337 Z00036 M55053
M31664 M31665 M31666 M31667
mon
rat A22562 B24406 P04799 K02422 K03241 M26127 X01031 1009215A
A20963 S16875 1105282A
1005270A
1203207A
ham S13885 JX0190 P24453 M63787 D10252 1803390B
PX0036 1705176C
gpi Q64391 D50457 U23501
rab B27821 P00187 D00213 M11728 X05686 X13853 1008260A
Q29526 M36538 1109280A
1204232A
1307202B
1501250A
dog B37222 1703408C
chi JT0575 Q01741 M64537 1708151A
tro Q92110 S69278
P79830 U62797
Cyp1a-2 mou A00186 B92495 P00186 X00479 M10022 X04283 K02589
A26373 B24953
CYP1A3 tro Q92109 S69277
P79829 U62796
CYP1A4 chi P79760 X99453
CYP1A5 chi P79761 X99454
CYP1A pla S34184 Q92100 X73631
CYP1A Ota Q92095 U14161 2113184A
CYP1A Sch Q92116 U14162 2113184B
CYP1A Chc Q92039 U19855
CYP1A Dla P79716 U78316
CYP1A Mto Q92148 L41886 L41917
CYP1B1 hum Q16678 U03688 2013283A
Q93089 U56438
rat I48130 Q64678 X83867 U09540 2113315A
Cyp1b-1 mou Q64461 X78445 2017226A
Q64429 U03283
Q60593 U02479
We use combined listing of GenBank, EMBL and DDBJ accession numbers because they use common numbering.
Some sequences can be identified from N-terminal sequences as belonging to a subfamily. These have been included in the listing of the subfamily even though it is premature to assign a specific number to these sequences.
Aal = Anopheles albimanus (mosquito) bab = baboon (Papio species) Bld = Blaberus discoidalis (cockroach) bov = bovine cat = cat (Felis catus) Cel = Caenorhabditis elegans (nematode worm) Chc = Chaetodon capistratus chi = chicken Dla = Dicentrarchus labrax (European sea bass) Dme = Drosophila melanogaster (fruit fly) dog = dog fro = bullfrog (Rana catesbeiana) gol = goldfish got = goat gpi = guinea pig ham = hamster Har = Helicoverpa armigera hor = horse hum = human Hvi = Heliothis virescens Ipu = Ictalurus punctatus (channel catfish) jqu = japanese quail Lst = Lymnaea stagnalis (pond snail) Mdo = Musca domestica (house fly) Mir = Macaca irus (crab-eating monkey) mon = monkey mou = mouse Mse = Manduca sexta (tobacco hornworm) Mto = Microgadus tomcod Ota = Opsanus tau (toadfish) pig = pig pla = Pleuronectes platessa (plaice) Ppx = Papilio polyxenes (black swallowtail butterfly) rab = rabbit rat = rat Rcu = Romanomermis culicivorax (nematode) Sch = Stenotomus chrysops (scup) she = sheep tro = trout
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